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Description Participants Agenda (TBA)

NIMBioS Investigative Workshop

Leptospirosis Modeling


Leptospira image.

Topic: Mathematical modeling of Leptospira infection, transmission, and intervention strategies

Meeting dates: June 3-5, 2014

Location: NIMBioS at the University of Tennessee, Knoxville

Claudia Munoz-Zanzi, Div. of Epidemiology and Community Health, School of Public Health, Univ. of Minnesota, Minneapolis
Michael Begon, Evolution, Ecology, and Behavior, Institute of Integrative Biology, Univ. of Liverpool
Xiaopeng Zhao, Mechanical, Aerospace and Biomedical Engineering, Univ. of Tennessee, Knoxville

Objectives: Leptospirosis is a zoonotic disease of global public health importance with complex transmission dynamics. This workshop will explore mathematical tools and approaches for describing 1) within-host dynamics of Leptospira infection and immunity in reservoir and incidental hosts; 2) multi-host, multi-species Leptospira transmission dynamics in urban and rural settings; and 3) environmental drivers of leptospirosis transmission in animals and people. The workshop will bring together expertise in bacteriology, molecular biology, epidemiology, statistics, veterinary medicine, human medicine, ecology, hydrology, mathematical modeling, network dynamics, evolutionary dynamics, and nonlinear analysis. Attendees will explore the state of knowledge of leptospirosis transmission in animal and human populations and the capabilities and limitations of the existing techniques that could be used for explaining currently available empirical data. Recommendations will then be made on the need for further empirical studies as well as future directions for modeling and analysis. As a result of this workshop, we will have an improved understanding of the conceptual models of Leptospira transmission in various ecological systems and of the gaps in data and methods. We will also established new collaborations and a common language between biologists and theorists interested in leptospirosis.

Descriptive Flyer

The application process is now closed.

NIMBioS Investigative Workshops focus on broad topics or a set of related topics, summarizing/synthesizing the state of the art and identifying future directions. Organizers and key invited researchers make up half the 30-40 participants in a workshop, and the remaining 15-20 participants are filled through open application from the scientific community. Open applicants selected to attend are notified by NIMBioS within two weeks of the application deadline. Investigative Workshops have the potential for leading to one or more future Working Groups. Individuals with a strong interest in the topic, including post-docs and graduate students, are encouraged to apply. If needed, NIMBioS can provide support (travel, meals, lodging) for Workshop attendees, whether from a non-profit or for-profit organization.