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Description Participants Agenda (TBA)

NIMBioS Investigative Workshop

Heart Rhythm Disorders

Cardiac image.

Topic: Mathematical Modeling of Heart Rhythm Disorders

Meeting dates: December 3-5, 2014

Location: NIMBioS at the University of Tennessee, Knoxville

Alena Talkachova, Biomedical Engineering, Univ. of Minnesota
John Wesley Cain, Mathematics and Computer Science, Univ. of Richmond, Virginia
Xiaopeng Zhao, Mechanical, Aerospace, and Biomedical Engineering, Univ. of Tennessee, Knoxville

Co-sponsored by: Institute of Biomedical Engineering (iBME), Univ. of Tennessee

Objectives: The heart is a complex nonlinear system, whose function involves the interaction between mechanical contractions of cardiac muscles and waves of electrical excitation propagating in the heart. Heartbeats are the result of the nonlinear coupling between these electrical and mechanical functions of the heart. Cardiovascular diseases, which are often associated with heart rhythm disorders, are the leading cause of death in the Western world. A complete understanding of heart rhythm disorders requires a complex system-level approach that incorporates the interaction between electrical, chemical, and mechanical activities of the heart on a variety of biological scales: ion channels to single cells to multi-cellular tissue to organ. Given the difficulty of monitoring and controlling all these factors in the lab, mathematical modeling provides a useful tool for this purpose. The goal of this workshop is to unite researchers from different disciplines – clinicians, mathematicians, physicists, biomedical engineers, and industrial practitioners – in order to better understand the existing mathematical challenges and to explore new directions in modeling of cardiovascular dynamics. As a result of the workshop, we will identify challenges and frontiers in mathematical modeling, statistics and prediction, dynamics and control, stability analysis, as well as data acquisition and analysis for heart rhythm related diseases. We will also foster new interdisciplinary collaborations.

Descriptive flyer

Heart Rhythm Disorders WordPress site.   NIMBioS has created a WordPress site to facilitate group communication and information sharing for the workshop. This is an interactive tool for sharing resources and comments before, during and after the meeting. All participants will receive an official email from WordPress inviting you to join the site. You will be asked to click on the link in the email from WordPress to accept the invitation. Before the meeting, we encourage you to introduce yourself to the rest of the group by writing a post with some details about your background and what you hope to gain from the meeting. Full details on how to post, comment and upload files to the WordPress site are available at the site (

The application process is now closed. Successful applicants will be notified within two weeks of the application deadline. If needed, financial support for travel, meals, and lodging is available for workshop attendees.

NIMBioS Investigative Workshops focus on broad topics or a set of related topics, summarizing/synthesizing the state of the art and identifying future directions. Organizers and key invited researchers make up half the 30-40 participants in a workshop, and the remaining 15-20 participants are filled through open application from the scientific community. Open applicants selected to attend are notified by NIMBioS within two weeks of the application deadline. Investigative Workshops have the potential for leading to one or more future Working Groups. Individuals with a strong interest in the topic, including post-docs and graduate students, are encouraged to apply. If needed, NIMBioS can provide support (travel, meals, lodging) for Workshop attendees.