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NIMBioS Tutorial

The Search for Selection

Topic: The Search for Selection

Meeting dates: June 3-7, 2019

Location: NIMBioS at the University of Tennessee, Knoxville

Organizer: J. Bruce Walsh, Ecology & Evolutionary Biology, Univ. of Arizona

Description

Biologists are obsessed (indeed, seduced) by the search for signatures of selection in organismal features of interest, ranging from specific traits to genome-wide signatures. A vast number of approaches have been suggested in this search for selection, including genomic-based signatures of recent or ongoing selection, tests based on either excessive amounts or nonrandom patterns of divergence (in both fossil sequences and functional genomics data) and the more classical Lande-Arnold fitness estimates (direct association of phenotypic values with fitness estimates) and their modern extensions (such as aster models). Given the breadth of such searches, a large amount of machinery has been developed, but is rarely presented in a unified fashion. This tutorial will present an integrated overview of all these approaches, highlighting common themes and divergent assumptions.

The goal of this tutorial is to expose investigators from all branches of biology to this rich menagerie of tests. The material is applicable for population geneticists, genome biologists, evolutionary ecologists, paleontologists, functional morphologists, and just about any biologist who ponders on how to formally demonstrate that a feature (or features) of interest might have been shaped by selection.

This tutorial is a repeat of the NIMBioS tutorial offered June 18-22, 2018.

Intended Audience. The intended audience is advanced graduate students, postdocs, and faculty with an interest in searching for targets of selection, be they particular genomic sequences or particular traits.  Given the breadth of this topic, the material would be of interest to individuals from functional genomics, population and evolutionary genetics, ecology, paleobiology, functional morphology, and statistics (as well as other fields).  Background required: some basic introduction to population and/or quantitative genetics.

Application Deadline: February 1, 2019
To apply, you must complete an application on our online registration system:

  1. Click here to access the system
  2. Login or register
  3. Complete your user profile (if you haven't already)
  4. Find this tutorial event under Current Events Open for Application and click on Apply

Participation in NIMBioS tutorials is by application only. Individuals with a strong interest in the topic are encouraged to apply, and successful applicants will be notified within several weeks after the application deadline. NIMBioS will cover lodging (5 nights) for out of town participants as well as breakfast and lunch for all participants each day at NIMBioS. Limited travel support is available for those with a demonstrated need. Applicants should indicate on the online application whether they need travel support.

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A goal of NIMBioS is to enhance the cadre of researchers capable of interdisciplinary efforts across mathematics and biology. As part of this goal, NIMBioS is committed to promoting diversity in all its activities. Diversity is considered in all its aspects, social and scientific, including gender, ethnicity, scientific field, career stage, geography and type of home institution. Questions regarding diversity issues should be directed to diversity@nimbios.org. You can read more about our Diversity Plan on our NIMBioS Policies web page. The NIMBioS building is fully handicapped accessible.


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NSF logo. NIMBioS is supported by the National Science Foundation through NSF Award #DBI-1300426, with additional support from The University of Tennessee, Knoxville. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.
 
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