Topic: The Search for Selection
Meeting dates: June 18-22, 2018
Location: NIMBioS at the University of Tennessee, Knoxville
Organizer: J. Bruce Walsh, Ecology & Evolutionary Biology, Univ. of Arizona
Biologists are obsessed (indeed, seduced) by the search for signatures of selection in organismal features of interest, ranging from specific traits to genome-wide signatures. A vast number of approaches have been suggested in this search for selection, including genomic-based signatures of recent or ongoing selection, tests based on either excessive amounts or nonrandom patterns of divergence (in both fossil sequences and functional genomics data) and the more classical Lande-Arnold fitness estimates (direct association of phenotypic values with fitness estimates) and their modern extensions (such as aster models). Given the breadth of such searches, a large amount of machinery has been developed, but is rarely presented in a unified fashion. This tutorial presents an integrated overview of all these approaches, highlighting common themes and divergent assumptions. (see Agenda for a list of lectures).
The goal of this tutorial is to expose investigators from all branches of biology to this rich menagerie of tests. It is applicable for population geneticists, genome biologists, evolutionary ecologists, paleontologists, functional morphologists, and just about any biologist who ponders on how to formally demonstrate that a feature (or features) of interest might have been shaped by selection.
Intended Audience. The intended audience is advanced graduate students, postdocs, and faculty with an interest in searching for targets of selection, be they particular genomic sequences or particular traits. Given the breadth of this topic, we expect students from functional genomics, population and evolutionary genetics, ecology, paleobiology, functional morphology, and statistics (as well as other fields). The background required is some basic introduction to population and/or quantitative genetics.
Descriptive Flyer (PDF)
Summary Report. TBA
The Search for Selection WordPress site
The Search for Selection WordPress site. NIMBioS has created a WordPress site to facilitate group communication and information sharing for the tutorial. This is an interactive tool for sharing resources and comments before, during and after the meeting. All participants will receive an official email from WordPress inviting you to join the site. You will be asked to click on the link in the email from WordPress to accept the invitation. Before the tutorial, we encourage you to introduce yourself to the rest of the group by writing a post with some details about your background and what you hope to gain from the meeting. Full details on how to post, comment and upload files to the WordPress site are available at the site (http://www.nimbios.org/wordpress-training/selection/).
Live Stream. The Tutorial will be streamed live. Note that NIMBioS tutorials involve open discussion and not necessarily a succession of talks. In addition, the schedule as posted may change during the Tutorial. To view the live stream, visit http://www.nimbios.org/videos/livestream.