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Quantitative Bioscience at the University of Tennessee

Cellular Biophysics

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The interdisciplinary physics frontier of cellular biophysics focuses on physical principles underlying cell function. Biophysicists develop mathematical and computational models to describe cellular functions and perform experiments to physically perturb cells and measure their mechanical responses. Studies have focused on observing complex structures inside cells, detecting cellular activities, and extending methods developed to study purified biological molecules to microscope-based cellular measurements. Combining novel experimental tools with mathematical models grounded in the physical sciences has enabled significant recent breakthroughs in the field.

Researcher Department Research Interests
S. Abel photo. Steve Abel
Chemical and Biomolecular Engineering Computational cell biology and immunology, theory and simulation of soft biological materials, membrane and polymer biophysics, systems biology
 photo. Vasilios Alexiades
Mathematics Math biology (chemotaxis, action potentials, phototransduction), phase change processes (laser ablation, solidification), CFD, parallel computing
 photo. Hong Guo
Biochemistry & Cellular and Molecular Biology Computational molecular and structural biology
M. Lavrentovich. Maxim Lavrentovich
Physics and Astronomy Theoretical biophysics, soft condensed matter physics
J. Mannik. Jaan Mannik
Physics and Astronomy Cellular biophysics, self-organizing processes in bacterial cell
RP McCord. Rachel Patton McCord
Biochemistry & Cellular and Molecular Biology 3D genome structure and the biophysics of cell migration
 photo. Andreas Nebenf├╝hr
Biochemistry & Cellular and Molecular Biology Cell biology of organelle movement in Arabidopsis
J. Smith. Jeremy Smith
Governor's Chair for Molecular Biophysics; Biochemistry & Cellular and Molecular Biology Computational molecular biophysics, supercomputing, neutrons, drug design. Director, Center for Molecular Biophysics, ORNL
S. Wise. Steven Wise
Mathematics Mathematical biology, computational materials science, computational and applied math

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From 2008 until early 2021, NIMBioS was supported by the National Science Foundation through NSF Award #DBI-1300426, with additional support from The University of Tennessee, Knoxville. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.
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