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Postdoctoral Fellowship in Computational Systems Biology at NIMBioS

The National Institute for Mathematical and Biological Synthesis (NIMBioS) and Department of Biochemistry & Cellular and Molecular Biology at the University of Tennessee, Knoxville, are currently accepting applications for a three-year postdoctoral fellowship in computational biology with an interest in using systems approaches to understand complex biological processes in cell biology, cancer biology, immunology or developmental biology.

An applicant may propose to use modeling, simulation, or analysis to produce useful biological information or concepts that current theories cannot provide. The proposed study should address biological problems involving dynamics and complexity of gene regulatory networks (GRNs) and/or the interplay between the GRNs and networks at the cellular level. While the applicant must propose an independent research project as part of the application, he/she will be expected to work closely with Dr. Tian Hong in UT's Department of Biochemistry & Cellular and Molecular Biology.

Examples of the biological topics of interest include, but are not limited to:

  • Cell cycle progression, cellular senescence, cell differentiation and death.
  • Plasticity of cells during development or cancer progression.
  • Cancer metastasis and dormancy.
  • Dynamical response of immune system (including response to viral infection).
  • Development of immune cells.
  • Embryonic development.

Examples of computational methods of interest include, but are not limited to:

  • Processing of omics data for dynamical modeling (e.g., genomic, transcriptomic, proteomic data).
  • Integration of multiscale data for dynamical modeling (e.g. transcriptomic, epigenomic, subcellular, cellular data).
  • Ordinary Differential Equation (ODE), Partial Differential Equation (PDE), and stochastic methods.
  • Multiscale modeling.
  • Parameter optimization.
  • Analysis using bifurcation theory, landscape theory, and statistical methods.

Support: Annual stipend of $51,000 and full University of Tennessee employee fringe benefits. Year 1 support will come from NIMBioS and includes a $3000 travel budget. Support for Years 2 and 3, assuming satisfactory performance, will come from the Department of Biochemistry & Cellular and Molecular Biology and Dr. Tian Hong.
    Hong Faculty Website
    Hong Lab Website

Deadline: Applications will be considered beginning April 2, 2017, continuing until the position is filled. Letters of recommendation should be submitted at the time of application.

For more information: Contact NIMBioS Associate Director Dr. Brian O'Meara (bomeara@utk.edu) or Dr. Tian Hong, Department of Biochemistry & Cellular and Molecular Biology (hongtian@utk.edu). See http://www.nimbios.org/postdocs/ for a detailed description of the NIMBioS Postdoctoral Fellowship program.

Application and Submission Process:

As part of the application process, you will be prompted to upload a detailed project description in a single PDF document, organized as follows:

  1. Cover sheet (~1 page)
    1. Descriptive Title
    2. Short Title (25 characters max)
    3. Name and contact information
    4. Project Summary (250 words max) - appropriate for public distribution on the NIMBioS web site
    5. Proposed start and end dates
    6. Potential conflicts of interest with the members of the Advisory Board or the NIMBioS Leadership Team.
  2. Problem statement - Clear and concise description of the research problem to be addressed, why it is important, and the approach to be used to address it. Include detail on mathematical and biological connections involved, and describe why your background is appropriate to address the problem. Include appropriate literature citations. This project description is an essential component of the application.
  3. Proposed activities that make use of NIMBioS opportunities to enhance the applicants abilities - include any particular outreach or educational activities planned. NIMBioS postdoctoral fellows typically have two local mentors (one more focused on biology and one more focused on mathematics). It is anticipated that Dr. Tian Hong will mentor the person in this position, and applicants should try to identify (if possible) another associated with NIMBioS, the University of Tennessee, or Oak Ridge National Laboratory.
  4. Names and contact information for three references. Please arrange for each reference to provide a letter of recommendation regarding your background and ability to carry out the independent research as proposed, and your ability to engage in collaborative research as part of NIMBioS community. These letters should be submitted directly by the letter writer by email to postdoc_app@nimbios.org. All letters of recommendation must be received before an application will be considered complete.
  5. Full CV.

Project descriptions, which include the Problem Statement and Proposed Activities sections and any figures and tables, are brief, not to exceed 5 single-spaced (12-pt type) pages (excluding cover sheet, literature citations, names and contact information of referees, and CV). The project description will be accepted in digital format only, as a single pdf file, including all of the components listed above (items 1-5). Graphics should be embedded directly into the pdf document.

Note that information contained in requests for NIMBioS support are governed by the NIMBioS Privacy Policy.

To Apply: You must complete an application on our online registration system:

  1. Click here to access the system
  2. Login or register
  3. Complete your user profile (if you haven't already)
  4. Find Postdoctoral Fellowships under Current Events Open for Application and click on Apply

Overview of the NIMBioS Postdoctoral Fellowship program
Helpful Tips for Postdoctoral Fellowship Applicants.



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FAX: (865) 974-9300
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NIMBioS is sponsored by the National Science Foundation through NSF Award #DBI-1300426, with additional support from The University of Tennessee, Knoxville. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.
 
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