NIMBioS supported several Sabbatical Fellows each year during the period 2010 – 2016. NIMBioS no longer provides financial support for Sabbatical Fellows, but continues to provide office space and a collaborative scientific environment for self-supported visitors. These individuals come to NIMBioS for visits of up to several months duration, with the length of stay determined by the objectives of the proposed project. For more information about self-supported visits and how to apply, click here.
(Mathematics, Univ. College London)
Project Title: Mathematical models of noise in cellular signalling networks
Karen Page researches the effects of noise in cellular signaling networks and investigates how the circuitry of molecular signals within the cells can ensure sharp boundaries in embryonic development. She is also interested in evolutionary dynamics and cancer modeling.
Sabbatical Dates: January - August 2011
Panovska-Griffiths J, Page KM, Briscoe J. 2013. A gene regulatory motif that generates oscillatory or multiway switch outputs. Journal of the Royal Society Interface, 10(79): 20120826. [Online]
Willis L, Graham TA, Alarcon T, Alison MR, Tomlinson IPM, Page KM. 2013. What can be learnt about disease progression in breast cancer dormancy from relapse data? PLoS ONE, 8(5): e62320. [Online]
Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V. 2012. Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell, 148(1-2): 273-284. [Online]
Krakauer DC, Page K, Flack J. 2011. The immuno-dynamics of conflict intervention in social systems. PLoS ONE 6(8): e22709. doi:10.1371/journal.pone.0022709 [Online]
(Biology, Indiana State Univ.)
Project Title: Development of new non-alignment phylogenomic methods for determining relationships at the species,subspecies, and population levels
Gary Stuart is working on a project to develop new analytical methods capable of comparing a high fraction of information present within a large number of highly related genomes for multiple purposes, including 1) the derivation of precise, data-rich estimates of phylogenetic relatedness, 2) the large-scale unambiguous assignment of genomic contents into gene families and subfamilies, 3) the identification of gene and/or genome content responsible for conflicting phylogenetic signals within genomes, 4) the establishment of quantitatively supported species/subspecies boundaries to improve documentation of taxonomic diversity and its phylogeographic distribution, and 5) the derivation of evolutionary models and population genomic parameters.
Sabbatical Dates: August - December 2011