Dates: August 2009 – October 2011
Project Title: Multiscale simulations of biomolecular systems
As a NIMBioS postdoctoral fellow, Yi Mao (Ph.D Physical Chemistry, Northwestern University, 2000) developed mathematical theories and algorithms to construct and integrate modeling and simulation at different scales for biomolecular systems. In particular, Mao focused on the enzymatic protein's role in biological energy production and the physical principles that drive protein evolution. Upon completing her fellowship at NIMBioS, Dr. Mao accepted a position as a senior fellow in the Department of Genome Sciences at the Univ. of Washington-Seattle.
NIMBioS Seminar: Dynamic modeling of proteins: physical basis for molecular evolution
Video Interview: The evolution of proteins
Publications while at NIMBioS
Mao Y. 2011. Dynamical Basis for Drug Resistance of HIV-1 Protease. BMC Structural Biology. Published [online] 8 July 2011.
Mao, Y. 2011. Dynamics studies of luciferase using elastic network model: how the sequence distribution of luciferase determines its color. Protein Engineering & Design Selection 2011, 24:341-349. [Online]
Presentations while at NIMBioS
Center for Discrete Mathematics and Computer Science (DIMACS), Rutgers University, 2011
University of Washington-Seattle, October 2011
University of Texas at El Paso, July 2011
Georgia Institute of Technology, March 2011
Biocomplexity Institute, University of Indiana, August 2010
Duke University, July 2010
Conference on Frontiers in Applied and Computational Mathematics, New Jersey Institute of Technology, June 2011 and May 2010
Q-bio Conference on Cellular Information Processing, Santa Fe, August 2011 and August 2010
Yeast Genetics and Molecular Biology Meeting, Vancouver, Canada, July 2010
The International School and Conference on Network Science, Boston, May 2010
Participation in NIMBioS Activities: Mao participated the NIMBioS Investigative Workshop: Synchrony in Biological Systems Across Scales and the NIMBioS Investigative Workshop: Graph Theory and Biological Networks
Collaborators: Jennifer Prescher (Chemistry, University of California-Irvine) on project, Engineering novel bioluminescence tools in biomedical research
Education, Outreach and Training
Mao gave a bioinformatics seminar (April 2011), Dynamic simulation of proteins: exploring the relationship between protein structure and function at Department of Mathematical Sciences, Univ. of Texas-El Paso, a minority-serving institution.
Mao participated NIMBioS Interdisciplinary Seminars; NIMBioS discussions on job search and interviews for postdocs; and grant-writing workshops organized by Office of Research, University of Tennessee